June 23, 2017

Cervical cancer mortality higher that previously thought

26 January 2017, 12:43 | Elizabeth Houston

According to the CBS, the Affordable Care Act took effect in the study's final years and give priority to prevention services including no-cost screenings for breast, colorectal and cervical cancers. Most cervical cancer cases occur in women who have never been screened with a Pap test or have not been screened in the past five years.

Kunle Odunsi, MD, PhD, Deputy Director and Chair of Gynecologic Oncology at Roswell Park, says, "The gap in incidence and death rates from cervical cancer based on racial disparities is a wake-up call, a call to action".

Sportscaster Erin Andrews has revealed she was diagnosed with cervical cancer in 2016, and went back to work just days after undergoing surgery to treat the condition. But routine screening can help prevent it. In the United States, there are 12,000 cases of cervical cancer each year and around 4,000 deaths.

The report was published in the January 24/31 issue of the Journal of the American Medical Association.

High rates of fatal breast cancers in women and prostate cancers in men - as well as cancers of the pancreas, colon and rectum in patients of both genders - clustered tightly in counties lying alongside the lower Mississippi River in Arkansas, Mississippi and Louisiana. Some 3,069 counties - out of a total of 3,142 - saw significant increases in liver cancer death rates, and numerous counties on the West Coast and in New Mexico and west Texas had much larger increases. Current guidelines do not recommend cervical cancer screening after the age of 65, since it was believed that older women were at much less risk. Most previous reports on geographic differences in cancer mortality in the USA have focused on variation by state, with less information available at the county level.

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Cervical cancer is 77 percent more deadly for black women and 44 percent more deadly for white women than previously thought, researchers report today in the journal Cancer.

Human papilloma virus (HPV) is known to be the most common sexually transmitted infection in the America.

Interestingly, a subset of eight cervical cancers were mostly HPV-negative and had molecular similarities to endometrial cancers. HPV is believed to cause more than 90 percent of anal and cervical cancers, 70 percent of vaginal and vulvar cancers and 60 percent of penile cancers.

"We need to continue to advocate for increased federal funding for cancer research". Surprisingly, new research from the Cancer Genome Atlas (TCGA) Research Network found that a subset of tumors did not show evidence of HPV infection, confirming that some cervical cancers are caused by genetic and other factors.

"Death rates differ dramatically between different types of cancers, and certain regions saw great progress in reducing cancer deaths and others fell behind", said lead researcher Dr. Christopher Murray.

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